Fighting Disease by Michaud & Feinstein

Ref: Michaud & Feinstein (1989). Fighting Disease: The Complete Guide to Natural Immune Power. Rodale Publishing.

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Summary­

  • The function of the immune system and how it fights off antigens.

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Immune System

  • Leukocytes: White Blood Cells (WBCs)

    • 80% Phagocytes (Neutrophil and Macrophages).

    • 20% Lymphocytes (B-Cells, T-Cells).

  • Non- Specialized (Phagocytes)

    • Neutrophils (Shock Cells): Comprise 60-75% of WBCs. They are the first to move to a wound to engage antigens; pus at the site of a wound is comprised of dead neutrophils.

    • Macrophage: Large WBCs that engulf antigens whole.

    • NK Cells: Fight off cells that have gone bad- tumor cells.

  • Specialized (Lymphocytes)

    • T-Cells: Live in the Thymus; they perforate the cell membrane of antigen protein coats, which shuts down the viral DNA copying. Some T-Cells watch the battle and make decisions while other T-Cells clone and fight, those that survive watch for the virus again and know how to respond. These cells patrol the body and search for any cell/organism without a protein code that is unique only to the self. T-Cells tell the immune system when to respond and how to respond.

    • B-Cells: Grow in Bone Marrow; they turn into plasma cells and create antibodies which inactivate antigens. Plasma cells can clone themselves and call in more macrophages and lymphocytes.

  • Immunodeficiency: loss of some or all of the immune system functions.

  • Auto-Immune Disease: When your cells attack your own body.

  • Bone Marrow: Produce Stem Cells

  • Mast Cells: Release Histamine; sneeze, runny nose, hives (urticaria).

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Pathogens

  • Pathogens: Bacteria, Viruses, Yeasts, Fungi, Parasites that invade a host and are regarded as a threat by the immune system and capable of stimulating an immune response.

    • Bacteria: Sits outside body cells and secretes toxins.

    • Virus: Removes protein coat to slip into nucleus of a cell and copy its DNA, when the cell dies, thousands of new viruses come out.

      • Human Immunodeficiency Virus (HIV): attacks helper T-Cells and clones itself.

  • Antigens: Proteins found on the surface of the pathogen.

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Endocrine System

  • Hormones: Chemical messengers that relay instructions from endocrine glands to the body.

    • Interleukin: Hormones that carry messengers from one immune system cell to another.

      • IL-1: Macrophage that has devoured an antigen invader. Brings on fever and induces fatigue.  

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